Cargando…

MiRNA‐199a‐5p targets WNT2 to regulate depression through the CREB/BDNF signaling in hippocampal neuron

INTRODUCTION: This study mainly investigated the role of miR‐199a‐5p in depression. METHODS: qRT‐PCR and western blotting were employed to detect the expressions of miR‐199a‐5p, CREB and BDNF. Sucrose preference test, forced swimming test, and tail suspension test were performed to evaluate depressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zheng, Yang, Jianli, Fang, Qing, Shao, Hua, Yang, Dalu, Sun, Junfang, Gao, Lizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413827/ https://www.ncbi.nlm.nih.gov/pubmed/34333859 http://dx.doi.org/10.1002/brb3.2107

Ejemplares similares

Knockdown of miR-124 Reduces Depression-like Behavior by Targeting CREB1 and BDNF
por: Yang, Wei, et al.
Publicado: (2020)

Exercise Prevents Memory Impairment Induced by Arsenic Exposure in Mice: Implication of Hippocampal BDNF and CREB
por: Sun, Bao-Fei, et al.
Publicado: (2015)

Alterations of Serum Levels of BDNF-Related miRNAs in Patients with Depression
por: Li, You-Jie, et al.
Publicado: (2013)

Oxytocin treatment improves dexamethasone‐induced depression‐like symptoms associated with enhancement of hippocampal CREB‐BDNF signaling in female mice
por: Mori, Masayoshi, et al.
Publicado: (2022)

CREB Activation Mediates Plasticity in Cultured Hippocampal Neurons
por: Segal, Menahem, et al.
Publicado: (1998)

Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways
por: Tu, Youbing, et al.
Publicado: (2019)

Neuronal Activity Regulates Hippocampal miRNA Expression
por: Eacker, Stephen M., et al.
Publicado: (2011)

Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling
por: Ko, Hyo Rim, et al.
Publicado: (2018)

Oncomirs miRNA-221/222 and Tumor Suppressors miRNA-199a/195 Are Crucial miRNAs in Liver Cancer: A Systematic Analysis
por: Li, Yanhu, et al.
Publicado: (2016)

Estrogen administration attenuates post-stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus
por: Jiang, Huigang, et al.
Publicado: (2021)

Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons
por: Bach, Svitlana V., et al.
Publicado: (2023)

Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling
por: Ruan, Jie, et al.
Publicado: (2019)

Xingnao Jieyu Decoction Ameliorates Poststroke Depression through the BDNF/ERK/CREB Pathway in Rats
por: Li, Tao, et al.
Publicado: (2018)

Identification of the miRNA targetome in hippocampal neurons using RIP-seq
por: Malmevik, Josephine, et al.
Publicado: (2015)

The BDNF effects on dendritic spines of mature hippocampal neurons depend on neuronal activity
por: Kellner, Yves, et al.
Publicado: (2014)

Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons
por: Dong, YiLong, et al.
Publicado: (2018)

GLP-1 plays a protective role in hippocampal neuronal cells by activating cAMP-CREB-BDNF signaling pathway against CORT+HG-induced toxicity
por: Ma, Qi, et al.
Publicado: (2023)

Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression
por: Zhang, Kuo, et al.
Publicado: (2023)

Farnesoid X Receptor-Mediated Cytoplasmic Translocation of CRTC2 Disrupts CREB-BDNF Signaling in Hippocampal CA1 and Leads to the Development of Depression-Like Behaviors in Mice
por: Hu, Wenfeng, et al.
Publicado: (2020)

Downregulation of miR-199b is associated with distant metastasis in colorectal cancer via activation of SIRT1 and inhibition of CREB/KISS1 signaling
por: Shen, Zhan-long, et al.
Publicado: (2016)

Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons
por: Palomer, Ernest, et al.
Publicado: (2016)

Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression
por: Wu, Jie, et al.
Publicado: (2006)

Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons
por: Cheung, Zelda H, et al.
Publicado: (2007)

High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons
por: Andreska, Thomas, et al.
Publicado: (2014)

Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons
por: Seifert, Bianca, et al.
Publicado: (2016)

Black Bamboo Rhizome Extract Improves Cognitive Dysfunction by Upregulating the Expression of Hippocampal BDNF and CREB in Rats with Cerebral Ischaemia-Reperfusion Injury
por: Yi, Chuan-An, et al.
Publicado: (2021)

Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis
por: Zohny, Sohir M., et al.
Publicado: (2023)

Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons
por: Pugazhenthi, Subbiah, et al.
Publicado: (2011)

Differential regulation of brain‐derived neurotrophic factor (BDNF) expression in sensory neuron axons by miRNA‐206
por: Shrestha, Shiva, et al.
Publicado: (2019)

Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures
por: van Spronsen, Myrrhe, et al.
Publicado: (2013)

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum
por: Asrari, Najmeh, et al.
Publicado: (2018)

The Kinase Function of MSK1 Regulates BDNF Signaling to CREB and Basal Synaptic Transmission, But Is Not Required for Hippocampal Long-Term Potentiation or Spatial Memory
por: Daumas, Stephanie, et al.
Publicado: (2017)

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice
por: Koh, Eun-Jeong, et al.
Publicado: (2017)

The Roles of BDNF, pCREB and Wnt3a in the Latent Period Preceding Activation of Progenitor Cell Mitosis in The Adult Dentate Gyrus by Fluoxetine
por: Pinnock, Scarlett B., et al.
Publicado: (2010)

BDNF Regulates the Expression and Distribution of Vesicular Glutamate Transporters in Cultured Hippocampal Neurons
por: Melo, Carlos V., et al.
Publicado: (2013)

Involvement of BDNF/TrkB and ERK/CREB axes in nitroglycerin-induced rat migraine and effects of estrogen on these signals in the migraine
por: Guo, Jiu-Qing, et al.
Publicado: (2016)

miR-199b, a novel tumor suppressor miRNA in acute myeloid leukemia with prognostic implications
por: Favreau, Amanda J., et al.
Publicado: (2016)

Yuk-Gunja-Tang attenuates neuronal death and memory impairment via ERK/CREB/BDNF signaling in the hippocampi of experimental Alzheimer’s disease model
por: Pak, Malk Eun, et al.
Publicado: (2022)

GPR39 (Zinc Receptor) Knockout Mice Exhibit Depression-Like Behavior and CREB/BDNF Down-Regulation in the Hippocampus
por: Młyniec, Katarzyna, et al.
Publicado: (2015)

Differential expression of miRNA199b-5p as a novel biomarker for sporadic and hereditary parathyroid tumors
por: Hwang, Sena, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7th4dm2id2s2jq2fqr5avmg45u