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Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus

One characteristic feature of mesial temporal lobe epilepsy is granule cell dispersion (GCD), a pathological widening of the granule cell layer in the dentate gyrus. The loss of the extracellular matrix protein Reelin, an important positional cue for neurons, correlates with GCD formation in MTLE pa...

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Detalles Bibliográficos
Autores principales: Orcinha, Catarina, Kilias, Antje, Paschen, Enya, Follo, Marie, Haas, Carola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414139/
https://www.ncbi.nlm.nih.gov/pubmed/34483838
http://dx.doi.org/10.3389/fnmol.2021.730811