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miR-135b-3p Promotes Cardiomyocyte Ferroptosis by Targeting GPX4 and Aggravates Myocardial Ischemia/Reperfusion Injury
Ferroptosis is a form of cell death induced by excess iron and accumulation of reactive oxygen species in cells. Recently, ferroptosis has been reported to be associated with cancer and ischemia/reperfusion (I/R) injury in multiple organs. However, the regulatory effects and underlying mechanisms of...
Autores principales: | Sun, Weixin, Shi, Ruijie, Guo, Jun, Wang, Haiyan, Shen, Le, Shi, Haibo, Yu, Peng, Chen, Xiaohu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414249/ https://www.ncbi.nlm.nih.gov/pubmed/34485394 http://dx.doi.org/10.3389/fcvm.2021.663832 |
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