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miR-135b-3p Promotes Cardiomyocyte Ferroptosis by Targeting GPX4 and Aggravates Myocardial Ischemia/Reperfusion Injury

Ferroptosis is a form of cell death induced by excess iron and accumulation of reactive oxygen species in cells. Recently, ferroptosis has been reported to be associated with cancer and ischemia/reperfusion (I/R) injury in multiple organs. However, the regulatory effects and underlying mechanisms of...

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Detalles Bibliográficos
Autores principales: Sun, Weixin, Shi, Ruijie, Guo, Jun, Wang, Haiyan, Shen, Le, Shi, Haibo, Yu, Peng, Chen, Xiaohu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414249/
https://www.ncbi.nlm.nih.gov/pubmed/34485394
http://dx.doi.org/10.3389/fcvm.2021.663832

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