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Adenovirus transduction to express human ACE2 causes obesity-specific morbidity in mice, impeding studies on the effect of host nutritional status on SARS-CoV-2 pathogenesis

The COVID-19 pandemic has paralyzed the global economy and resulted in millions of deaths globally. People with co-morbidities like obesity, diabetes and hypertension are at an increased risk for severe COVID-19 illness. This is of overwhelming concern because 42% of Americans are obese, 30% are pre...

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Detalles Bibliográficos
Autores principales: Rai, Pallavi, Chuong, Christina, LeRoith, Tanya, Smyth, James W., Panov, Julia, Levi, Moshe, Kehn-Hall, Kylene, Duggal, Nisha K., Lucarelli, James-Weger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414371/
https://www.ncbi.nlm.nih.gov/pubmed/34509029
http://dx.doi.org/10.1016/j.virol.2021.08.014

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