Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine

[Image: see text] Many neurodegenerative diseases are associated with the self-assembly of peptides and proteins into fibrillar aggregates. Soluble misfolded oligomers formed during the aggregation process, or released by mature fibrils, play a relevant role in neurodegenerative processes through th...

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Detalles Bibliográficos
Autores principales: Errico, Silvia, Ramshini, Hassan, Capitini, Claudia, Canale, Claudio, Spaziano, Martina, Barbut, Denise, Calamai, Martino, Zasloff, Michael, Oropesa-Nuñez, Reinier, Vendruscolo, Michele, Chiti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414483/
https://www.ncbi.nlm.nih.gov/pubmed/34382791
http://dx.doi.org/10.1021/acschemneuro.1c00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414483/
https://www.ncbi.nlm.nih.gov/pubmed/34382791
http://dx.doi.org/10.1021/acschemneuro.1c00327

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