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Basal Synaptic Transmission and Long-Term Plasticity at CA3-CA1 Synapses Are Unaffected in Young Adult PINK1-Deficient Rats

Loss of function mutations in PARK6, the gene that encodes the protein PTEN-induced kinase 1 (PINK1), cause autosomal recessive familial Parkinson’s disease (PD). While PD is clinically diagnosed by its motor symptoms, recent studies point to the impact of non-motor symptoms, including cognitive dys...

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Detalles Bibliográficos
Autores principales:	Memon, Adeel A., Bagley, Micah E., Creed, Rose B., Amara, Amy W., Goldberg, Matthew S., McMahon, Lori L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414523/ https://www.ncbi.nlm.nih.gov/pubmed/34483814 http://dx.doi.org/10.3389/fnins.2021.655901

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