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Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease

Glucocorticoids (GCs) are widely used immunosuppressive drugs for autoimmune diseases, although considerable gaps exist between current knowledge of the mechanisms of GCs and their conclusive immune-regulatory effects. Here we generated a single-cell transcriptional immune cell atlas based on predni...

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Detalles Bibliográficos
Autores principales: Li, He, Gao, Yuehan, Xie, Lihui, Wang, Rong, Duan, Runping, Li, Zhaohuai, Chen, Binyao, Zhu, Lei, Wang, Xianggui, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414592/
https://www.ncbi.nlm.nih.gov/pubmed/34484247
http://dx.doi.org/10.3389/fimmu.2021.739605