Simvastatin does not alleviate muscle pathology in a mouse model of Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is an incurable disease, caused by the mutations in the DMD gene, encoding dystrophin, an actin-binding cytoskeletal protein. Lack of functional dystrophin results in muscle weakness, degeneration, and as an outcome cardiac and respiratory failure. As th...

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Detalles Bibliográficos
Autores principales: Mucha, Olga, Podkalicka, Paulina, Kaziród, Katarzyna, Samborowska, Emilia, Dulak, Józef, Łoboda, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414747/
https://www.ncbi.nlm.nih.gov/pubmed/34479633
http://dx.doi.org/10.1186/s13395-021-00276-3

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