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Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors
Sensorineural hearing loss is prevalent within society affecting the quality of life of 460 million worldwide. In the majority of cases, this is due to insult or degeneration of mechanosensory hair cells in the cochlea. In adult mammals, hair cell loss is irreversible as sensory cells are not replac...
Autores principales: | Erni, Silvia T., Gill, John C., Palaferri, Carlotta, Fernandes, Gabriella, Buri, Michelle, Lazarides, Katherine, Grandgirard, Denis, Edge, Albert S. B., Leib, Stephen L., Roccio, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414802/ https://www.ncbi.nlm.nih.gov/pubmed/34485296 http://dx.doi.org/10.3389/fcell.2021.710159 |
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