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Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis

OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as...

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Detalles Bibliográficos
Autores principales: Han, Junfeng, Yuan, Long, Li, Jianguo, Liang, Chunbao, Zhang, Dong, Mei, Zaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414940/
https://www.ncbi.nlm.nih.gov/pubmed/34463564
http://dx.doi.org/10.1177/03000605211035889
Descripción
Sumario:OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. RESULTS: The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. CONCLUSIONS: TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications.