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Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414940/ https://www.ncbi.nlm.nih.gov/pubmed/34463564 http://dx.doi.org/10.1177/03000605211035889 |
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author | Han, Junfeng Yuan, Long Li, Jianguo Liang, Chunbao Zhang, Dong Mei, Zaoxian |
author_facet | Han, Junfeng Yuan, Long Li, Jianguo Liang, Chunbao Zhang, Dong Mei, Zaoxian |
author_sort | Han, Junfeng |
collection | PubMed |
description | OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. RESULTS: The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. CONCLUSIONS: TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications. |
format | Online Article Text |
id | pubmed-8414940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-84149402021-09-04 Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis Han, Junfeng Yuan, Long Li, Jianguo Liang, Chunbao Zhang, Dong Mei, Zaoxian J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. RESULTS: The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. CONCLUSIONS: TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications. SAGE Publications 2021-08-31 /pmc/articles/PMC8414940/ /pubmed/34463564 http://dx.doi.org/10.1177/03000605211035889 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Han, Junfeng Yuan, Long Li, Jianguo Liang, Chunbao Zhang, Dong Mei, Zaoxian Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis |
title | Transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
title_full | Transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
title_fullStr | Transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
title_full_unstemmed | Transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
title_short | Transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
title_sort | transbronchial tuberculosis cavity plugging therapy for pulmonary
tuberculosis |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414940/ https://www.ncbi.nlm.nih.gov/pubmed/34463564 http://dx.doi.org/10.1177/03000605211035889 |
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