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Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis

OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as...

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Autores principales: Han, Junfeng, Yuan, Long, Li, Jianguo, Liang, Chunbao, Zhang, Dong, Mei, Zaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414940/
https://www.ncbi.nlm.nih.gov/pubmed/34463564
http://dx.doi.org/10.1177/03000605211035889
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author Han, Junfeng
Yuan, Long
Li, Jianguo
Liang, Chunbao
Zhang, Dong
Mei, Zaoxian
author_facet Han, Junfeng
Yuan, Long
Li, Jianguo
Liang, Chunbao
Zhang, Dong
Mei, Zaoxian
author_sort Han, Junfeng
collection PubMed
description OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. RESULTS: The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. CONCLUSIONS: TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications.
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spelling pubmed-84149402021-09-04 Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis Han, Junfeng Yuan, Long Li, Jianguo Liang, Chunbao Zhang, Dong Mei, Zaoxian J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. METHODS: One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. RESULTS: The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. CONCLUSIONS: TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications. SAGE Publications 2021-08-31 /pmc/articles/PMC8414940/ /pubmed/34463564 http://dx.doi.org/10.1177/03000605211035889 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Han, Junfeng
Yuan, Long
Li, Jianguo
Liang, Chunbao
Zhang, Dong
Mei, Zaoxian
Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title_full Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title_fullStr Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title_full_unstemmed Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title_short Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
title_sort transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414940/
https://www.ncbi.nlm.nih.gov/pubmed/34463564
http://dx.doi.org/10.1177/03000605211035889
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