Case Report: Identification of Two Rare Fusions, PDK1-ALK and STRN-ALK, That Coexist in a Lung Adenocarcinoma Patient and the Response to Alectinib

Several double ALK fusions coexisting in one patient have been reported. However, few studies have reported the clinical efficacy of ALK inhibitors in rare double ALK fusions. Here, we described a rare PDK1-ALK, STRN-ALK double-fusion variant in a patient with metastatic lung adenocarcinoma. The pat...

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Detalles Bibliográficos
Autores principales: Zeng, Hao, Li, Yalun, Wang, Ye, Huang, Meijuan, Zhang, Yan, Tian, Panwen, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415000/
https://www.ncbi.nlm.nih.gov/pubmed/34485156
http://dx.doi.org/10.3389/fonc.2021.722843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415000/
https://www.ncbi.nlm.nih.gov/pubmed/34485156
http://dx.doi.org/10.3389/fonc.2021.722843

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