Cargando…
Transcriptional Analysis of Infection With Early or Late Isolates From the 2013–2016 West Africa Ebola Virus Epidemic Does Not Suggest Attenuated Pathogenicity as a Result of Genetic Variation
The 2013–2016 West Africa Ebola virus (EBOV) epidemic caused by the EBOV-Makona isolate is the largest and longest recorded to date. It incurred over 28,000 infections and ∼11,000 deaths. Early in this epidemic, several mutations in viral glycoprotein (A82V), nucleoprotein (R111C), and polymerase L...
Autores principales: | Maroney, Kevin J., Pinski, Amanda N., Marzi, Andrea, Messaoudi, Ilhem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415004/ https://www.ncbi.nlm.nih.gov/pubmed/34484156 http://dx.doi.org/10.3389/fmicb.2021.714817 |
Ejemplares similares
-
Distinct transcriptional responses to fatal Ebola virus infection in cynomolgus and rhesus macaques suggest species-specific immune responses
por: Pinski, Amanda N., et al.
Publicado: (2021) -
Spatiotemporal variability in case fatality ratios for the 2013–2016 Ebola epidemic in West Africa
por: Forna, Alpha, et al.
Publicado: (2020) -
Perspectives on West Africa Ebola Virus Disease Outbreak, 2013–2016
por: Spengler, Jessica R., et al.
Publicado: (2016) -
Mathematical modeling of the West Africa Ebola epidemic
por: Chretien, Jean-Paul, et al.
Publicado: (2015) -
Dynamics of Ebola epidemics in West Africa 2014
por: Evans, Robin J., et al.
Publicado: (2015)