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Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature
Primary bone lymphoma (PBL) is a less frequent type of extranodal lymphoma, which is defined as a single skeletal tumor or multiple bone lesions without visceral or lymph node involvement. Most published cases have reported diffused large B cell lymphoma (DLBCL) of PBL, and the prognosis is good aft...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415166/ https://www.ncbi.nlm.nih.gov/pubmed/34485126 http://dx.doi.org/10.3389/fonc.2021.690819 |
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author | Yu, Suli Xu, Jianqiang |
author_facet | Yu, Suli Xu, Jianqiang |
author_sort | Yu, Suli |
collection | PubMed |
description | Primary bone lymphoma (PBL) is a less frequent type of extranodal lymphoma, which is defined as a single skeletal tumor or multiple bone lesions without visceral or lymph node involvement. Most published cases have reported diffused large B cell lymphoma (DLBCL) of PBL, and the prognosis is good after conventional treatment. Primary T-cell lymphoma is extremely rare in the literature. The clinical symptoms, imaging findings, diagnosis, treatment and prognosis of primary T-cell lymphoma of bone are still unclear. The case details a young male patient who was treated for bone tuberculosis and was diagnosed with T-cell lymphoma during an open surgical biopsy. Further imaging evidence showed the lymphoma was localized within the femur. The patient responded poorly to combined chemo- and radiotherapy. He was confirmed with local lung metastases 11 months later and died at the 17th month of onset. I would like to provide PBL entities with some rare information about primary bone peripheral T-cell lymphoma and discuss the best strategy for the treatment of rare PBL subtypes. |
format | Online Article Text |
id | pubmed-8415166 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84151662021-09-04 Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature Yu, Suli Xu, Jianqiang Front Oncol Oncology Primary bone lymphoma (PBL) is a less frequent type of extranodal lymphoma, which is defined as a single skeletal tumor or multiple bone lesions without visceral or lymph node involvement. Most published cases have reported diffused large B cell lymphoma (DLBCL) of PBL, and the prognosis is good after conventional treatment. Primary T-cell lymphoma is extremely rare in the literature. The clinical symptoms, imaging findings, diagnosis, treatment and prognosis of primary T-cell lymphoma of bone are still unclear. The case details a young male patient who was treated for bone tuberculosis and was diagnosed with T-cell lymphoma during an open surgical biopsy. Further imaging evidence showed the lymphoma was localized within the femur. The patient responded poorly to combined chemo- and radiotherapy. He was confirmed with local lung metastases 11 months later and died at the 17th month of onset. I would like to provide PBL entities with some rare information about primary bone peripheral T-cell lymphoma and discuss the best strategy for the treatment of rare PBL subtypes. Frontiers Media S.A. 2021-08-09 /pmc/articles/PMC8415166/ /pubmed/34485126 http://dx.doi.org/10.3389/fonc.2021.690819 Text en Copyright © 2021 Yu and Xu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Yu, Suli Xu, Jianqiang Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title | Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title_full | Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title_fullStr | Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title_full_unstemmed | Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title_short | Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature |
title_sort | imaging features of primary t cell lymphoma in bone: a case report and review of literature |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415166/ https://www.ncbi.nlm.nih.gov/pubmed/34485126 http://dx.doi.org/10.3389/fonc.2021.690819 |
work_keys_str_mv | AT yusuli imagingfeaturesofprimarytcelllymphomainboneacasereportandreviewofliterature AT xujianqiang imagingfeaturesofprimarytcelllymphomainboneacasereportandreviewofliterature |