Cargando…

MicroRNAs hsa-miR-618 and hsa-miR-297 Might Modulate the Pleiotropic Effects Exerted by Statins in Endothelial Cells Through the Inhibition of ROCK2 Kinase: in-silico Approach

Several studies show that statin therapy improves endothelial function by cholesterol-independent mechanisms called “pleiotropic effects.” These are due to the inhibition of the RhoA/ROCK kinase pathway, its inhibition being an attractive atheroprotective treatment. In addition, recent work has show...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leal, Karla, Saavedra, Kathleen, Rebolledo, Camilo, Salazar, Luis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415262/ https://www.ncbi.nlm.nih.gov/pubmed/34485404 http://dx.doi.org/10.3389/fcvm.2021.704175

Ejemplares similares

Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer
por: Lopes, Camile B., et al.
Publicado: (2018)

“Seed-Milarity” Confers to hsa-miR-210 and hsa-miR-147b Similar Functional Activity
por: Bertero, Thomas, et al.
Publicado: (2012)

Clustered microRNAs hsa-miR-221-3p/hsa-miR-222-3p and their targeted genes might be prognostic predictors for hepatocellular carcinoma
por: Wang, Xiangkun, et al.
Publicado: (2019)

MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME)
por: Petty, Robert D., et al.
Publicado: (2016)

Expression Analysis of hsa-miR-181a-5p, hsa-miR-143-3p, hsa-miR-132-3p and hsa-miR-23a-3p as Biomarkers in Colorectal Cancer—Relationship to the Body Mass Index
por: Tesolato, Sofía Elena, et al.
Publicado: (2023)

Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome
por: Tao, Wenhua, et al.
Publicado: (2016)

Diagnostic Significance of hsa-miR-21-5p, hsa-miR-192-5p, hsa-miR-155-5p, hsa-miR-199a-5p Panel and Ratios in Hepatocellular Carcinoma on Top of Liver Cirrhosis in HCV-Infected Patients
por: Eldosoky, Mona A., et al.
Publicado: (2023)

CeRNA network identified hsa-miR-17-5p, hsa-miR-106a-5p and hsa-miR-2355-5p as potential diagnostic biomarkers for tuberculosis
por: Song, Jie, et al.
Publicado: (2023)

Hsa-let-7c-5p, hsa-miR-130b-3p, and hsa-miR-142-3p as Novel miRNA Biomarkers for Melanoma Progression
por: Wu, Xuerui, et al.
Publicado: (2022)

Qualitative and quantitative assessment of sperm miRNAs identifies hsa-miR-9-3p, hsa-miR-30b-5p and hsa-miR-122-5p as potential biomarkers of male infertility and sperm quality
por: Joshi, Meghali, et al.
Publicado: (2022)

The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer
por: Poduval, Deepak, et al.
Publicado: (2020)

hsa-miR-518-5p/hsa-miR-3135b Regulates the REL/SOD2 Pathway in Ischemic Cerebral Infarction
por: Zhao, Boyan, et al.
Publicado: (2022)

Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma
por: Feng, Linxiang, et al.
Publicado: (2023)

Epigenetic inactivation of the hsa-miR-203 in haematological malignancies
por: Chim, Chor Sang, et al.
Publicado: (2011)

Novel small RNA expression libraries uncover hsa-miR-30b and hsa-miR-30c as important factors in anoikis resistance
por: Moreno-Mateos, Miguel A., et al.
Publicado: (2013)

Gestational Diabetes Mellitus Regulatory Network Identifies hsa-miR-145-5p and hsa-miR-875-5p as Potential Biomarkers
por: Zamanian Azodi, Mona, et al.
Publicado: (2019)

hsa-miR-96 and hsa-miR-217 Expression Down-Regulates with Increasing Dysplasia in Pancreatic Intraepithelial Neoplasias and Intraductal Papillary Mucinous Neoplasms
por: Chang, XiaoYan, et al.
Publicado: (2017)

Correction: The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer
por: Poduval, Deepak, et al.
Publicado: (2021)

Hsa-miR-15a and Hsa-miR-16-1 Expression Is Not Related to Proliferation Centers Abundance and Other Prognostic Factors in Chronic Lymphocytic Leukemia
por: Rossi, Maura, et al.
Publicado: (2013)

hsa-miR-3177-5p and hsa-miR-3178 Inhibit 5-HT1A Expression by Binding the 3′-UTR Region in vitro
por: Wu, Xue, et al.
Publicado: (2019)

Cancer Cells’ Metabolism Dynamics in Renal Cell Carcinoma Patients’ Outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186
por: Morais, Mariana, et al.
Publicado: (2021)

The Highlighted Roles of Metabolic and Cellular Response to Stress Pathways Engaged in Circulating hsa-miR-494-3p and hsa-miR-661 in Alzheimer’s Disease
por: Hojati, Zohreh, et al.
Publicado: (2021)

Identification of Circulating hsa-miR-324-3p and hsa-miR-331-3p Exchanges in The Serum of Alzheimer’s Patients and Insights into The Pathophysiological Pathways
por: Heydari, Maryam, et al.
Publicado: (2021)

Expression profiles of hsa-miR-148a-3p and hsa-miR-125b-5p in human breast milk and infant formulae
por: Chiba, Takeshi, et al.
Publicado: (2022)

Atrophic gastritis and gastric cancer tissue miRNome analysis reveals hsa-miR-129-1 and hsa-miR-196a as potential early diagnostic biomarkers
por: Varkalaite, Greta, et al.
Publicado: (2022)

Exploration of the Hsa-miR-1587–Protein Interaction and the Inhibition to CASK
por: Zhang, Lulu, et al.
Publicado: (2021)

Hsa-miR-665 Is a Promising Biomarker in Cancer Prognosis
por: Guan, Xuefeng, et al.
Publicado: (2023)

Hsa_circ_0041268 promotes NSCLC progress by sponging miR‐214‐5p/ROCK1
por: Yang, Wenhui, et al.
Publicado: (2022)

Hsa_circ_0101432 promotes the development of hepatocellular carcinoma (HCC) by adsorbing miR-1258 and miR-622
por: Zou, Haibo, et al.
Publicado: (2019)

Amplification and Overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in Medulloblastoma
por: Lu, Yuan, et al.
Publicado: (2009)

Hsa-miR-5581-3p and Hsa-miR-542-3p Target the F8 Gene in Hemophilia A without F8 Mutations
por: Meng, Feiying
Publicado: (2021)

Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis
por: Gil-Martínez, Marta, et al.
Publicado: (2023)

Hsa-miR-181a-5p, hsa-miR-182-5p, and hsa-miR-26a-5p as potential biomarkers for BCR-ABL1 among adult chronic myeloid leukemia treated with tyrosine kinase inhibitors at the molecular response
por: Mohd Yacob, Aliza, et al.
Publicado: (2022)

hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
por: Liang, Jian, et al.
Publicado: (2021)

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism—The Young Finns Study
por: Raitoharju, Emma, et al.
Publicado: (2016)

Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer
por: Weber, David, et al.
Publicado: (2018)

Hsa-miR-34a-5p and hsa-miR-375 as Biomarkers for Monitoring the Effects of Drug Treatment for Migraine Pain in Children and Adolescents: A Pilot Study
por: Gallelli, Luca, et al.
Publicado: (2019)

Serum Extracellular Vesicle-Derived hsa-miR-2277-3p and hsa-miR-6813-3p Are Potential Biomarkers for Major Depression: A Preliminary Study
por: Seki, Issei, et al.
Publicado: (2023)

microRNA hsa-miR-425-5p and hsa-miR-4523 expressions as biomarkers of active pulmonary tuberculosis, latent tuberculosis infection, and lymph node tuberculosis
por: Massi, Muhammad Nasrum, et al.
Publicado: (2023)

The potential role of hsa_circ_0001079 in androgenetic alopecia via sponging hsa‐miR‐136‐5p
por: Wei, Hanxiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1t67td3ud30ggikclvtgbmnft9