Cargando…

Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility

Objective: This study aims to investigate the clinical efficacy of laparoscopy and hysteroscopy in the treatment of tubal-factor infertility (TFI) to provide a basis for predicting postoperative pregnancy rates. Methods: The clinical data of 336 patients who underwent laparoscopy and hysteroscopy fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Nian, Lei, Yang, De-Hong, Zhang, Jie, Zhao, Han, Zhu, Cai-Fen, Dong, Ming-Feng, Ai, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415305/
https://www.ncbi.nlm.nih.gov/pubmed/34485341
http://dx.doi.org/10.3389/fmed.2021.712222
_version_ 1783747941229395968
author Nian, Lei
Yang, De-Hong
Zhang, Jie
Zhao, Han
Zhu, Cai-Fen
Dong, Ming-Feng
Ai, Ying
author_facet Nian, Lei
Yang, De-Hong
Zhang, Jie
Zhao, Han
Zhu, Cai-Fen
Dong, Ming-Feng
Ai, Ying
author_sort Nian, Lei
collection PubMed
description Objective: This study aims to investigate the clinical efficacy of laparoscopy and hysteroscopy in the treatment of tubal-factor infertility (TFI) to provide a basis for predicting postoperative pregnancy rates. Methods: The clinical data of 336 patients who underwent laparoscopy and hysteroscopy for TFI between February 2018 and December 2018 in the Department of Reproductive Gynecology at the First People's Hospital of Yunnan were retrospectively analyzed. After implementing the inclusion and exclusion criteria, 278 patients were included in the study. The patients were grouped according to pelvic adhesions, hydrosalpinx, twisted fallopian tubes, and fimbriae structure. The impact of the extent of fallopian tube diseases on postoperative pregnancy outcomes was analyzed. Results: Of the 278 patients, 129 got pregnant (pregnancy rate = 46.4%). Pelvic adhesions, hydrosalpinx, twisted/folded fallopian tubes, and damage to the fimbriae of the fallopian tubes were found to affect the natural pregnancy rate after surgery, and it decreased significantly with the aggravation of the disease (P < 0.001). Of the 129 patients who had natural pregnancies, 29 had ectopic pregnancies (ectopic pregnancy rate = 22.48%). Twisted/folded fallopian tubes and damage to the fimbriae structure significantly increased the incidence of postoperative ectopic pregnancy (P < 0.001). Conclusion: Laparoscopy and hysteroscopy are effective treatments for TFI. Pelvic adhesions, twisted/folded fallopian tubes, hydrosalpinx, and damage to the fimbriae of the fallopian tubes can affect postoperative pregnancy outcomes and lead to failure of a natural pregnancy after the operation. The incidence of ectopic pregnancy increases with the degree of fallopian tube twisting/folding and the degree of damage to the fimbriae of the fallopian tubes.
format Online
Article
Text
id pubmed-8415305
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-84153052021-09-04 Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility Nian, Lei Yang, De-Hong Zhang, Jie Zhao, Han Zhu, Cai-Fen Dong, Ming-Feng Ai, Ying Front Med (Lausanne) Medicine Objective: This study aims to investigate the clinical efficacy of laparoscopy and hysteroscopy in the treatment of tubal-factor infertility (TFI) to provide a basis for predicting postoperative pregnancy rates. Methods: The clinical data of 336 patients who underwent laparoscopy and hysteroscopy for TFI between February 2018 and December 2018 in the Department of Reproductive Gynecology at the First People's Hospital of Yunnan were retrospectively analyzed. After implementing the inclusion and exclusion criteria, 278 patients were included in the study. The patients were grouped according to pelvic adhesions, hydrosalpinx, twisted fallopian tubes, and fimbriae structure. The impact of the extent of fallopian tube diseases on postoperative pregnancy outcomes was analyzed. Results: Of the 278 patients, 129 got pregnant (pregnancy rate = 46.4%). Pelvic adhesions, hydrosalpinx, twisted/folded fallopian tubes, and damage to the fimbriae of the fallopian tubes were found to affect the natural pregnancy rate after surgery, and it decreased significantly with the aggravation of the disease (P < 0.001). Of the 129 patients who had natural pregnancies, 29 had ectopic pregnancies (ectopic pregnancy rate = 22.48%). Twisted/folded fallopian tubes and damage to the fimbriae structure significantly increased the incidence of postoperative ectopic pregnancy (P < 0.001). Conclusion: Laparoscopy and hysteroscopy are effective treatments for TFI. Pelvic adhesions, twisted/folded fallopian tubes, hydrosalpinx, and damage to the fimbriae of the fallopian tubes can affect postoperative pregnancy outcomes and lead to failure of a natural pregnancy after the operation. The incidence of ectopic pregnancy increases with the degree of fallopian tube twisting/folding and the degree of damage to the fimbriae of the fallopian tubes. Frontiers Media S.A. 2021-08-16 /pmc/articles/PMC8415305/ /pubmed/34485341 http://dx.doi.org/10.3389/fmed.2021.712222 Text en Copyright © 2021 Nian, Yang, Zhang, Zhao, Zhu, Dong and Ai. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Nian, Lei
Yang, De-Hong
Zhang, Jie
Zhao, Han
Zhu, Cai-Fen
Dong, Ming-Feng
Ai, Ying
Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title_full Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title_fullStr Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title_full_unstemmed Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title_short Analysis of the Clinical Efficacy of Laparoscopy and Hysteroscopy in the Treatment of Tubal-Factor Infertility
title_sort analysis of the clinical efficacy of laparoscopy and hysteroscopy in the treatment of tubal-factor infertility
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415305/
https://www.ncbi.nlm.nih.gov/pubmed/34485341
http://dx.doi.org/10.3389/fmed.2021.712222
work_keys_str_mv AT nianlei analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT yangdehong analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT zhangjie analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT zhaohan analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT zhucaifen analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT dongmingfeng analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility
AT aiying analysisoftheclinicalefficacyoflaparoscopyandhysteroscopyinthetreatmentoftubalfactorinfertility