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Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
Piwi-interacting RNAs (piRNAs) constitute a class of small RNAs that bind PIWI proteins and are essential to repress transposable elements in the animal germline, thereby promoting genome stability and maintaining fertility. C. elegans piRNAs (21U RNAs) are transcribed individually from minigenes as...
Autores principales: | Perez-Borrajero, Cecilia, Podvalnaya, Nadezda, Holleis, Kay, Lichtenberger, Raffael, Karaulanov, Emil, Simon, Bernd, Basquin, Jérôme, Hennig, Janosch, Ketting, René F., Falk, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415317/ https://www.ncbi.nlm.nih.gov/pubmed/34413138 http://dx.doi.org/10.1101/gad.348648.121 |
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