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Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans

Piwi-interacting RNAs (piRNAs) constitute a class of small RNAs that bind PIWI proteins and are essential to repress transposable elements in the animal germline, thereby promoting genome stability and maintaining fertility. C. elegans piRNAs (21U RNAs) are transcribed individually from minigenes as...

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Detalles Bibliográficos
Autores principales: Perez-Borrajero, Cecilia, Podvalnaya, Nadezda, Holleis, Kay, Lichtenberger, Raffael, Karaulanov, Emil, Simon, Bernd, Basquin, Jérôme, Hennig, Janosch, Ketting, René F., Falk, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415317/
https://www.ncbi.nlm.nih.gov/pubmed/34413138
http://dx.doi.org/10.1101/gad.348648.121

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