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[(18)F]PBR146 and [(18)F]DPA-714 in vivo Imaging of Neuroinflammation in Chronic Hepatic Encephalopathy Rats

Neuroinflammation is an important pathogenesis of hepatic encephalopathy (HE). The upregulation of translocator protein (TSPO) during neuroinflammation provides an imaging molecular target to evaluate the severity of neuroinflammation in chronic HE rats. [18F]DPA-714 and [18F]PBR146 targeting TSPO a...

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Detalles Bibliográficos
Autores principales: Kong, Xiang, Luo, Song, Wang, Yun Fei, Yang, Gui Fen, Lu, Guang Ming, Zhang, Long Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415356/
https://www.ncbi.nlm.nih.gov/pubmed/34483820
http://dx.doi.org/10.3389/fnins.2021.678144