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Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain

Transposable elements (TEs) account for more than 50% of the human genome and many have been co-opted throughout evolution to provide regulatory functions for gene expression networks. Several lines of evidence suggest that these networks are fine-tuned by the largest family of TE controllers, the K...

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Detalles Bibliográficos
Autores principales: Playfoot, Christopher J., Duc, Julien, Sheppard, Shaoline, Dind, Sagane, Coudray, Alexandre, Planet, Evarist, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415367/
https://www.ncbi.nlm.nih.gov/pubmed/34400477
http://dx.doi.org/10.1101/gr.275133.120