Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases

The X Chromosome plays an important role in human development and disease. However, functional genomic and disease association studies of X genes greatly lag behind autosomal gene studies, in part owing to the unique biology of X-Chromosome inactivation (XCI). Because of XCI, most genes are only exp...

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Detalles Bibliográficos
Autores principales: Sauteraud, Renan, Stahl, Jill M., James, Jesica, Englebright, Marisa, Chen, Fang, Zhan, Xiaowei, Carrel, Laura, Liu, Dajiang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415373/
https://www.ncbi.nlm.nih.gov/pubmed/34426515
http://dx.doi.org/10.1101/gr.275677.121

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