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Genome-wide variability in recombination activity is associated with meiotic chromatin organization
Recombination enables reciprocal exchange of genomic information between parental chromosomes and successful segregation of homologous chromosomes during meiosis. Errors in this process lead to negative health outcomes, whereas variability in recombination rate affects genome evolution. In mammals,...
Autores principales: | Jin, Xiaofan, Fudenberg, Geoff, Pollard, Katherine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415379/ https://www.ncbi.nlm.nih.gov/pubmed/34301629 http://dx.doi.org/10.1101/gr.275358.121 |
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