Cargando…
Biased Coupling to β-Arrestin of Two Common Variants of the CB(2) Cannabinoid Receptor
β-arrestins are partners of the G protein-coupled receptors (GPCRs), regulating their intracellular trafficking and signaling. Development of biased GPCR agonists, selectively targeting either G protein or β-arrestin pathways, are in the focus of interest due to their therapeutic potential in differ...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415483/ https://www.ncbi.nlm.nih.gov/pubmed/34484125 http://dx.doi.org/10.3389/fendo.2021.714561 |