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Biased Coupling to β-Arrestin of Two Common Variants of the CB(2) Cannabinoid Receptor

β-arrestins are partners of the G protein-coupled receptors (GPCRs), regulating their intracellular trafficking and signaling. Development of biased GPCR agonists, selectively targeting either G protein or β-arrestin pathways, are in the focus of interest due to their therapeutic potential in differ...

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Detalles Bibliográficos
Autores principales:	Turu, Gábor, Soltész-Katona, Eszter, Tóth, András Dávid, Juhász, Cintia, Cserző, Miklós, Misák, Ádám, Balla, András, Caron, Marc G., Hunyady, László
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415483/ https://www.ncbi.nlm.nih.gov/pubmed/34484125 http://dx.doi.org/10.3389/fendo.2021.714561

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