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Circulating Maternal sFLT1 (Soluble fms-Like Tyrosine Kinase-1) Is Sufficient to Impair Spiral Arterial Remodeling in a Preeclampsia Mouse Model

One driving factor for developing preeclampsia—a pregnancy disorder, often associated with poor spiral artery (SpA)-remodeling and fetal growth restriction—is the anti-angiogenic sFLT1 (soluble fms-like tyrosine kinase-1), which is found to be highly upregulated in preeclampsia patients. The sFLT1-m...

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Detalles Bibliográficos
Autores principales:	Vogtmann, Rebekka, Heupel, Jacqueline, Herse, Florian, Matin, Mahsa, Hagmann, Henning, Bendix, Ivo, Kräker, Kristin, Dechend, Ralf, Winterhager, Elke, Kimmig, Rainer, Köninger, Angela, Gellhaus, Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415521/ https://www.ncbi.nlm.nih.gov/pubmed/34397280 http://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17567

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