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Lipid Metabolism Regulates Oxidative Stress and Ferroptosis in RAS-Driven Cancers: A Perspective on Cancer Progression and Therapy

HRAS, NRAS and KRAS, collectively referred to as oncogenic RAS, are the most frequently mutated driver proto-oncogenes in cancer. Oncogenic RAS aberrantly rewires metabolic pathways promoting the generation of intracellular reactive oxygen species (ROS). In particular, lipids have gained increasing...

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Detalles Bibliográficos
Autores principales:	Bartolacci, Caterina, Andreani, Cristina, El-Gammal, Yasmin, Scaglioni, Pier Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415548/ https://www.ncbi.nlm.nih.gov/pubmed/34485382 http://dx.doi.org/10.3389/fmolb.2021.706650

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