Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neurogenesis

The dentate gyrus of the hippocampus and the subventricular zone are neurogenic niches where neural stem and progenitor cells replicate throughout life to generate new neurons. The Btg1 gene maintains the stem cells of the neurogenic niches in quiescence. The deletion of Btg1 leads to an early trans...

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Detalles Bibliográficos
Autores principales: Micheli, Laura, Creanza, Teresa Maria, Ceccarelli, Manuela, D’Andrea, Giorgio, Giacovazzo, Giacomo, Ancona, Nicola, Coccurello, Roberto, Scardigli, Raffaella, Tirone, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415876/
https://www.ncbi.nlm.nih.gov/pubmed/34485283
http://dx.doi.org/10.3389/fcell.2021.696684

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