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Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report
RATIONALE: Cerebral venous sinus thrombosis associated with protein S deficiency is rare in adolescent patients and has high disability and fatality. Patient concerns: A 15-year-old male student presented in the hospital with sudden headache, nausea, and vomiting and was diagnosed with protein S def...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415943/ https://www.ncbi.nlm.nih.gov/pubmed/34477132 http://dx.doi.org/10.1097/MD.0000000000027024 |
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author | Peng, Tao Zhang, Zini Zu, Bifeng Dan, Bitang |
author_facet | Peng, Tao Zhang, Zini Zu, Bifeng Dan, Bitang |
author_sort | Peng, Tao |
collection | PubMed |
description | RATIONALE: Cerebral venous sinus thrombosis associated with protein S deficiency is rare in adolescent patients and has high disability and fatality. Patient concerns: A 15-year-old male student presented in the hospital with sudden headache, nausea, and vomiting and was diagnosed with protein S deficiency by gene testing. DIAGNOSES: Cerebral venous sinus thrombosis due to protein S deficiency was diagnosed in this adolescent patient, who underwent successful endovascular therapy (EVT). INTERVENTIONS: The patient was treated with standard anti-coagulation therapy including low-molecular-weight heparin (90 IU/kg/Q12 h) and dehydrant (mannitol 125 mL Q8 h); however, the symptoms were not alleviated. Successful EVT was implemented. OUTCOMES: Both the superior sagittal sinus and bilateral transverse sinus were recanalized after thrombus clearance. The patient achieved a complete recovery without any other stroke recurrence during follow-up. LESSONS: EVT can be performed with favorable and effective clinical outcomes in adolescent cerebral venous sinus thrombosis patients with protein S deficiency. EVT associated with standard anti-coagulation therapy may improve the prognosis and reduce mortality among such patients. |
format | Online Article Text |
id | pubmed-8415943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-84159432021-09-07 Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report Peng, Tao Zhang, Zini Zu, Bifeng Dan, Bitang Medicine (Baltimore) 5300 RATIONALE: Cerebral venous sinus thrombosis associated with protein S deficiency is rare in adolescent patients and has high disability and fatality. Patient concerns: A 15-year-old male student presented in the hospital with sudden headache, nausea, and vomiting and was diagnosed with protein S deficiency by gene testing. DIAGNOSES: Cerebral venous sinus thrombosis due to protein S deficiency was diagnosed in this adolescent patient, who underwent successful endovascular therapy (EVT). INTERVENTIONS: The patient was treated with standard anti-coagulation therapy including low-molecular-weight heparin (90 IU/kg/Q12 h) and dehydrant (mannitol 125 mL Q8 h); however, the symptoms were not alleviated. Successful EVT was implemented. OUTCOMES: Both the superior sagittal sinus and bilateral transverse sinus were recanalized after thrombus clearance. The patient achieved a complete recovery without any other stroke recurrence during follow-up. LESSONS: EVT can be performed with favorable and effective clinical outcomes in adolescent cerebral venous sinus thrombosis patients with protein S deficiency. EVT associated with standard anti-coagulation therapy may improve the prognosis and reduce mortality among such patients. Lippincott Williams & Wilkins 2021-09-03 /pmc/articles/PMC8415943/ /pubmed/34477132 http://dx.doi.org/10.1097/MD.0000000000027024 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 5300 Peng, Tao Zhang, Zini Zu, Bifeng Dan, Bitang Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title | Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title_full | Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title_fullStr | Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title_full_unstemmed | Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title_short | Successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: A case report |
title_sort | successful endovascular therapy for an adolescent patient with cerebral venous sinus thrombosis: a case report |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415943/ https://www.ncbi.nlm.nih.gov/pubmed/34477132 http://dx.doi.org/10.1097/MD.0000000000027024 |
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