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A retrospective study on the preventive effect of statin after carotid artery stenting

This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS). Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatmen...

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Autores principales: Liu, Wen, Zhao, Xiong-fei, Liang, Ya-long, Jiang, Chao, Hou, Li-xia, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416008/
https://www.ncbi.nlm.nih.gov/pubmed/34477113
http://dx.doi.org/10.1097/MD.0000000000026201
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author Liu, Wen
Zhao, Xiong-fei
Liang, Ya-long
Jiang, Chao
Hou, Li-xia
Chen, Xiao
author_facet Liu, Wen
Zhao, Xiong-fei
Liang, Ya-long
Jiang, Chao
Hou, Li-xia
Chen, Xiao
author_sort Liu, Wen
collection PubMed
description This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS). Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatment) and control group (routine treatment), each group 50 patients. Outcomes consisted of degree of nerve defect (as measured by National Institute of Health Stroke Scale), lipid profiles (mg/dL), and CAS complications within 30 days after surgery. After treatment, there were no significant differences in National Institute of Health Stroke Scale, lipid profiles, and mortality rate between 2 groups. However, significant differences in total cholesterol (mg/dL, P = .03), low-density lipoprotein (mg/dL, P = .01), transient ischemic attack (P = .03), ischemic stroke (P = .04), and cardiac complications (P = .03) were identified within 30 days after CAS between 2 groups. The results of this study showed that prior statin treatment may be effective for the prevention of CAS complications.
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spelling pubmed-84160082021-09-07 A retrospective study on the preventive effect of statin after carotid artery stenting Liu, Wen Zhao, Xiong-fei Liang, Ya-long Jiang, Chao Hou, Li-xia Chen, Xiao Medicine (Baltimore) 3800 This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS). Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatment) and control group (routine treatment), each group 50 patients. Outcomes consisted of degree of nerve defect (as measured by National Institute of Health Stroke Scale), lipid profiles (mg/dL), and CAS complications within 30 days after surgery. After treatment, there were no significant differences in National Institute of Health Stroke Scale, lipid profiles, and mortality rate between 2 groups. However, significant differences in total cholesterol (mg/dL, P = .03), low-density lipoprotein (mg/dL, P = .01), transient ischemic attack (P = .03), ischemic stroke (P = .04), and cardiac complications (P = .03) were identified within 30 days after CAS between 2 groups. The results of this study showed that prior statin treatment may be effective for the prevention of CAS complications. Lippincott Williams & Wilkins 2021-09-03 /pmc/articles/PMC8416008/ /pubmed/34477113 http://dx.doi.org/10.1097/MD.0000000000026201 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 3800
Liu, Wen
Zhao, Xiong-fei
Liang, Ya-long
Jiang, Chao
Hou, Li-xia
Chen, Xiao
A retrospective study on the preventive effect of statin after carotid artery stenting
title A retrospective study on the preventive effect of statin after carotid artery stenting
title_full A retrospective study on the preventive effect of statin after carotid artery stenting
title_fullStr A retrospective study on the preventive effect of statin after carotid artery stenting
title_full_unstemmed A retrospective study on the preventive effect of statin after carotid artery stenting
title_short A retrospective study on the preventive effect of statin after carotid artery stenting
title_sort retrospective study on the preventive effect of statin after carotid artery stenting
topic 3800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416008/
https://www.ncbi.nlm.nih.gov/pubmed/34477113
http://dx.doi.org/10.1097/MD.0000000000026201
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