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Methyl Ferulic Acid Attenuates Human Cardiac Fibroblasts Differentiation and Myocardial Fibrosis by Suppressing pRB-E2F1/CCNE2 and RhoA/ROCK2 Pathway

Background: Myocardial fibrosis is a key pathological process after myocardial infarction, which leads to poor outcomes in patients at the end stage. Effective treatments for improving prognosis of myocardial fibrosis are needed to be further developed. Methyl ferulic acid (MFA), a biologically acti...

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Detalles Bibliográficos
Autores principales: Liao, Rongheng, Qi, Zhen, Tang, Ri, Wang, Renrong, Wang, Yongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416034/
https://www.ncbi.nlm.nih.gov/pubmed/34483923
http://dx.doi.org/10.3389/fphar.2021.714390