Crucial Mutations of Spike Protein on SARS-CoV-2 Evolved to Variant Strains Escaping Neutralization of Convalescent Plasmas and RBD-Specific Monoclonal Antibodies

Small number of SARS-CoV-2 epidemic lineages did not efficiently exhibit a neutralization profile, while single amino acid mutation in the spike protein has not been confirmed in altering viral antigenicity resulting in immune escape. To identify crucial mutations in spike protein that escape humora...

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Detalles Bibliográficos
Autores principales: Ding, Chengchao, He, Jun, Zhang, Xiangyu, Jiang, Chengcheng, Sun, Yong, Zhang, Yuqing, Chen, Qingqing, He, Hongliang, Li, Wenting, Xie, Jiajia, Liu, Zhirong, Gao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416052/
https://www.ncbi.nlm.nih.gov/pubmed/34484190
http://dx.doi.org/10.3389/fimmu.2021.693775

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