Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center

Memory B cells and antibody-secreting plasma cells are generated within germinal centers during affinity maturation in which B-cell proliferation, selection, differentiation, and self-renewal play important roles. The mechanisms behind memory B cell and plasma cell differentiation in germinal center...

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Detalles Bibliográficos
Autores principales: Merino Tejero, Elena, Lashgari, Danial, García-Valiente, Rodrigo, He, Jiaojiao, Robert, Philippe A., Meyer-Hermann, Michael, Guikema, Jeroen E. J., Hoefsloot, Huub, van Kampen, Antoine H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416073/
https://www.ncbi.nlm.nih.gov/pubmed/34484219
http://dx.doi.org/10.3389/fimmu.2021.716240

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