Cargando…

Calpain 6 inhibits autophagy in inflammatory environments: A preliminary study on myoblasts and a chronic kidney disease rat model

A non-classical calpain, calpain 6 (CAPN6), can inhibit skeletal muscle differentiation and regeneration. In the present study, the role of CAPN6 in the regulation of the autophagy of myoblasts in vitro was investigated. The underlying molecular events and the CAPN6 level in atrophic skeletal muscle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yue Yue, Gu, Li Jie, Zhu, Nan, Wang, Ling, Cai, Min Chao, Jia, Jie Shuang, Rong, Shu, Yuan, Wei Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416137/ https://www.ncbi.nlm.nih.gov/pubmed/34435644 http://dx.doi.org/10.3892/ijmm.2021.5027

Ejemplares similares

Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation
por: Luo, Zhi-Wen, et al.
Publicado: (2021)

Calpain proteolytic systems counteract endothelial cell adaptation to inflammatory environments
por: Miyazaki, Takuro, et al.
Publicado: (2020)

Calpains in cyanobacteria and the origin of calpains
por: Vešelényiová, Dominika, et al.
Publicado: (2022)

Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2
por: Zhang, Yuanyuan, et al.
Publicado: (2017)

Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney disease
por: Zhang, Yue-yue, et al.
Publicado: (2018)

Regulatory role of calpain in neuronal death
por: Cheng, Si-ying, et al.
Publicado: (2018)

Influence of Capsaicin on Inflammatory Cytokines Induced by Lipopolysaccharide in Myoblast Cells Under In vitro Environment
por: Shang, Ke, et al.
Publicado: (2017)

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity
por: Menzies, F M, et al.
Publicado: (2015)

Specific calpain inhibition protects kidney against inflammaging
por: Hanouna, Guillaume, et al.
Publicado: (2017)

Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification
por: Wang, Yuan-Mei, et al.
Publicado: (2022)

Calpain activation and progression of inflammatory cycles in Parkinson’s disease
por: Gao, Andrew, et al.
Publicado: (2022)

Pro-Inflammatory Mediation of Myoblast Proliferation
por: Otis, Jeffrey S., et al.
Publicado: (2014)

Calpain-2 participates in the process of calpain-1 inactivation
por: Shinkai-Ouchi, Fumiko, et al.
Publicado: (2020)

Effect of a low-protein diet supplemented with keto-acids on autophagy and inflammation in 5/6 nephrectomized rats
por: Zhang, Yue-yue, et al.
Publicado: (2015)

Bacterial calpains and the evolution of the calpain (C2) family of peptidases
por: Rawlings, Neil D.
Publicado: (2015)

Novel calpain families and novel mechanisms for calpain regulation in Aplysia
por: Hastings, Margaret H., et al.
Publicado: (2017)

Commentary on: Calpain-2 participates in the process of calpain-1 inactivation
por: Kumari, Raniki, et al.
Publicado: (2021)

Requirement for PINCH in skeletal myoblast differentiation
por: Liao, Huimin, et al.
Publicado: (2022)

Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death
por: Wang, Yubin, et al.
Publicado: (2020)

Calpain-Mediated Cleavage of Calcineurin in Puromycin Aminonucleoside-Induced Podocyte Injury
por: Ding, Fangrui, et al.
Publicado: (2016)

Calpain-1 and Calpain-2 in the Brain: Dr. Jekill and Mr Hyde?
por: Baudry, Michel
Publicado: (2019)

Akirin1 promotes myoblast differentiation by modulating multiple myoblast differentiation factors
por: Sun, Wenqiang, et al.
Publicado: (2019)

MicroRNA-137 Inhibited Hypoxia-Induced Proliferation of Pulmonary Artery Smooth Muscle Cells by Targeting Calpain-2
por: Ge, Xiao-Yue, et al.
Publicado: (2021)

Deficiency of calpain-6 inhibits primary ciliogenesis
por: Kim, Bo Hye, et al.
Publicado: (2019)

Role of Calpain in Apoptosis
por: Momeni, Hamid Reza
Publicado: (2011)

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo
por: Russo, R, et al.
Publicado: (2011)

Calpain 2-mediated autophagy defect increases susceptibility of fatty livers to ischemia–reperfusion injury
por: Zhao, Q, et al.
Publicado: (2016)

Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages
por: Cui, Wei, et al.
Publicado: (2015)

Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease
por: Wang, Shu-Ling, et al.
Publicado: (2018)

Enriched environment boosts the post-stroke recovery of neurological function by promoting autophagy
por: Deng, Yi-Hao, et al.
Publicado: (2020)

Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer
por: Peng, Peike, et al.
Publicado: (2016)

Effect and mechanism of calpains on pediatric lobar pneumonia
por: Yin, Genquan, et al.
Publicado: (2016)

Calcium Signaling Mediates Cell Death and Crosstalk with Autophagy in Kidney Disease
por: Ning, Bo, et al.
Publicado: (2021)

Metabolomic Analysis of Trehalose Alleviating Oxidative Stress in Myoblasts
por: Zhang, Shuya, et al.
Publicado: (2023)

Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes
por: Wang, Chao, et al.
Publicado: (2017)

Postmortem role of calpain in Chinese and Wuzong goose muscles
por: Chang, Ya-Shiou, et al.
Publicado: (2019)

Killing Two Angry Birds with One Stone: Autophagy Activation by Inhibiting Calpains in Neurodegenerative Diseases and Beyond
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2019)

Calpain Dysregulation in Alzheimer's Disease
por: Ferreira, Adriana
Publicado: (2012)

Conformationally restricted calpain inhibitors
por: Adams, S. E., et al.
Publicado: (2015)

Role of Calpain-1 in Neurogenesis
por: Baudry, Michel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k7jsd94ifrdkim0ghv34msk2cp