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Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics

The autophagy-lysosome system allows cells to adapt to environmental changes by regulating the degradation and recycling of cellular components, and to maintain homeostasis by removing aggregated proteins and defective organelles. Cyclin G-associated kinase (GAK) is involved in the regulation of cla...

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Detalles Bibliográficos
Autores principales:	Miyazaki, Masaya, Hiramoto, Masaki, Takano, Naoharu, Kokuba, Hiroko, Takemura, Jun, Tokuhisa, Mayumi, Hino, Hirotsugu, Kazama, Hiromi, Miyazawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416139/ https://www.ncbi.nlm.nih.gov/pubmed/34468012 http://dx.doi.org/10.3892/ijmm.2021.5028

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