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Oxymatrine attenuates oxidized low-density lipoprotein-induced HUVEC injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via the activation of the SIRT1/Nrf2 signaling pathway

Oxymatrine, a quinolizidine alkaloid isolated from the traditional Chinese herb Sophora flavescens Aiton, has been demonstrated to exert anti-inflammatory and atherosclerotic effects, but the molecular mechanism has yet to be elucidated. Accumulating evidence indicates an important role of NLR famil...

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Detalles Bibliográficos
Autores principales:	Jin, Xin, Fu, Wan, Zhou, Jiaxiu, Shuai, Niannian, Yang, Yan, Wang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416146/ https://www.ncbi.nlm.nih.gov/pubmed/34368883 http://dx.doi.org/10.3892/ijmm.2021.5020

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