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Modulation of Peripheral CD4(+)CD25(+)Foxp3(+) Regulatory T Cells Ameliorates Surgical Stress-Induced Atherosclerotic Plaque Progression in ApoE-Deficient Mice

Systemic inflammation associated with major surgery rapidly accelerates atherosclerotic plaque progression in mice. Regulatory T cells (Tregs) have emerged as important modulators of atherogenesis. In coronary artery disease patients, low frequency of Tregs constitutes an independent risk factor for...

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Detalles Bibliográficos
Autores principales: Handke, Jessica, Kummer, Laura, Weigand, Markus A., Larmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416168/
https://www.ncbi.nlm.nih.gov/pubmed/34485396
http://dx.doi.org/10.3389/fcvm.2021.682458