Insights into the Implications of Coexisting Type 2 Inflammatory Diseases

The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associat...

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Autores principales: McCormick, Justin P, Lee, Jivianne T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416183/
https://www.ncbi.nlm.nih.gov/pubmed/34511966
http://dx.doi.org/10.2147/JIR.S311640
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author McCormick, Justin P
Lee, Jivianne T
author_facet McCormick, Justin P
Lee, Jivianne T
author_sort McCormick, Justin P
collection PubMed
description The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes.
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spelling pubmed-84161832021-09-09 Insights into the Implications of Coexisting Type 2 Inflammatory Diseases McCormick, Justin P Lee, Jivianne T J Inflamm Res Review The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes. Dove 2021-08-30 /pmc/articles/PMC8416183/ /pubmed/34511966 http://dx.doi.org/10.2147/JIR.S311640 Text en © 2021 McCormick and Lee. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
McCormick, Justin P
Lee, Jivianne T
Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_full Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_fullStr Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_full_unstemmed Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_short Insights into the Implications of Coexisting Type 2 Inflammatory Diseases
title_sort insights into the implications of coexisting type 2 inflammatory diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416183/
https://www.ncbi.nlm.nih.gov/pubmed/34511966
http://dx.doi.org/10.2147/JIR.S311640
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