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Drug-Induced Liver Disturbance During the Treatment of COVID-19

An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, at the end of 2019. The World Health Organization named the resulting infectious disease as coronavirus disease-2019 (COVID-19). Many studies concluded that patients infected with SARS-CoV-2 have di...

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Autores principales: Zhai, Guanghua, Li, Meifen, Wang, Ying, Wu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416279/
https://www.ncbi.nlm.nih.gov/pubmed/34483929
http://dx.doi.org/10.3389/fphar.2021.719308
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author Zhai, Guanghua
Li, Meifen
Wang, Ying
Wu, Jian
author_facet Zhai, Guanghua
Li, Meifen
Wang, Ying
Wu, Jian
author_sort Zhai, Guanghua
collection PubMed
description An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, at the end of 2019. The World Health Organization named the resulting infectious disease as coronavirus disease-2019 (COVID-19). Many studies concluded that patients infected with SARS-CoV-2 have different degrees of liver disturbance. However, the relationship between the drugs used for COVID-19 treatment and liver disturbance remains controversial. It is essential to evaluate the potential liver damage caused by various drugs in order to help guide clinical practice. This review analyzed the effect of drugs on hepatic function during the treatment of COVID-19.
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spelling pubmed-84162792021-09-04 Drug-Induced Liver Disturbance During the Treatment of COVID-19 Zhai, Guanghua Li, Meifen Wang, Ying Wu, Jian Front Pharmacol Pharmacology An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, at the end of 2019. The World Health Organization named the resulting infectious disease as coronavirus disease-2019 (COVID-19). Many studies concluded that patients infected with SARS-CoV-2 have different degrees of liver disturbance. However, the relationship between the drugs used for COVID-19 treatment and liver disturbance remains controversial. It is essential to evaluate the potential liver damage caused by various drugs in order to help guide clinical practice. This review analyzed the effect of drugs on hepatic function during the treatment of COVID-19. Frontiers Media S.A. 2021-08-18 /pmc/articles/PMC8416279/ /pubmed/34483929 http://dx.doi.org/10.3389/fphar.2021.719308 Text en Copyright © 2021 Zhai, Li, Wang and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Zhai, Guanghua
Li, Meifen
Wang, Ying
Wu, Jian
Drug-Induced Liver Disturbance During the Treatment of COVID-19
title Drug-Induced Liver Disturbance During the Treatment of COVID-19
title_full Drug-Induced Liver Disturbance During the Treatment of COVID-19
title_fullStr Drug-Induced Liver Disturbance During the Treatment of COVID-19
title_full_unstemmed Drug-Induced Liver Disturbance During the Treatment of COVID-19
title_short Drug-Induced Liver Disturbance During the Treatment of COVID-19
title_sort drug-induced liver disturbance during the treatment of covid-19
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416279/
https://www.ncbi.nlm.nih.gov/pubmed/34483929
http://dx.doi.org/10.3389/fphar.2021.719308
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