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Inactivation of SARS-CoV-2 by β-propiolactone causes aggregation of viral particles and loss of antigenic potential

Inactivated viral preparations are important resources in vaccine and antisera industry. Of the many vaccines that are being developed against COVID-19, inactivated whole-virus vaccines are also considered effective. β-propiolactone (BPL) is a widely used chemical inactivator of several viruses. Her...

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Detalles Bibliográficos
Autores principales:	Gupta, Divya, Parthasarathy, Haripriya, Sah, Vishal, Tandel, Dixit, Vedagiri, Dhiviya, Reddy, Shashikala, Harshan, Krishnan H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416322/ https://www.ncbi.nlm.nih.gov/pubmed/34487766 http://dx.doi.org/10.1016/j.virusres.2021.198555

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