A Facile Procedure for One-Pot Stable Conjugation of Two Proglucagon Cysteine-Containing Peptide Analogs

Optimization of peptides for therapeutic purposes often includes chemical conjugation or modification with substituents that serve to broaden pharmacology or improve pharmacokinetics. We report a convenient and rapid procedure for one-pot, site-specific conjugation of two cysteine-containing peptide...

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Detalles Bibliográficos
Autores principales: He, Rongjun, Mowery, Stephanie A., Chabenne, Joseph, Finan, Brian, Mayer, John P., DiMarchi, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416343/
https://www.ncbi.nlm.nih.gov/pubmed/34484114
http://dx.doi.org/10.3389/fendo.2021.693958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416343/
https://www.ncbi.nlm.nih.gov/pubmed/34484114
http://dx.doi.org/10.3389/fendo.2021.693958

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