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A Facile Procedure for One-Pot Stable Conjugation of Two Proglucagon Cysteine-Containing Peptide Analogs
Optimization of peptides for therapeutic purposes often includes chemical conjugation or modification with substituents that serve to broaden pharmacology or improve pharmacokinetics. We report a convenient and rapid procedure for one-pot, site-specific conjugation of two cysteine-containing peptide...
Autores principales: | He, Rongjun, Mowery, Stephanie A., Chabenne, Joseph, Finan, Brian, Mayer, John P., DiMarchi, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416343/ https://www.ncbi.nlm.nih.gov/pubmed/34484114 http://dx.doi.org/10.3389/fendo.2021.693958 |
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