Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal

Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte ce...

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Autores principales: Shah, Sangam, Ojha, Rajeev, Sitaula, Sanjeeta, Regmi, Dosti, Karn, Ragesh, Gajurel, Bikram Prasad, Rajbhandari, Reema, Gautam, Niraj, Paudel, Sunanda, Shrestha, Aashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416391/
https://www.ncbi.nlm.nih.gov/pubmed/34484845
http://dx.doi.org/10.1155/2021/8100423
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author Shah, Sangam
Ojha, Rajeev
Sitaula, Sanjeeta
Regmi, Dosti
Karn, Ragesh
Gajurel, Bikram Prasad
Rajbhandari, Reema
Gautam, Niraj
Paudel, Sunanda
Shrestha, Aashish
author_facet Shah, Sangam
Ojha, Rajeev
Sitaula, Sanjeeta
Regmi, Dosti
Karn, Ragesh
Gajurel, Bikram Prasad
Rajbhandari, Reema
Gautam, Niraj
Paudel, Sunanda
Shrestha, Aashish
author_sort Shah, Sangam
collection PubMed
description Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal.
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spelling pubmed-84163912021-09-04 Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal Shah, Sangam Ojha, Rajeev Sitaula, Sanjeeta Regmi, Dosti Karn, Ragesh Gajurel, Bikram Prasad Rajbhandari, Reema Gautam, Niraj Paudel, Sunanda Shrestha, Aashish Case Rep Neurol Med Case Report Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal. Hindawi 2021-08-26 /pmc/articles/PMC8416391/ /pubmed/34484845 http://dx.doi.org/10.1155/2021/8100423 Text en Copyright © 2021 Sangam Shah et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shah, Sangam
Ojha, Rajeev
Sitaula, Sanjeeta
Regmi, Dosti
Karn, Ragesh
Gajurel, Bikram Prasad
Rajbhandari, Reema
Gautam, Niraj
Paudel, Sunanda
Shrestha, Aashish
Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title_full Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title_fullStr Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title_full_unstemmed Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title_short Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal
title_sort recurrent bilateral optic neuritis associated with myelin oligodendrocyte glycoprotein antibody: a case report from nepal
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416391/
https://www.ncbi.nlm.nih.gov/pubmed/34484845
http://dx.doi.org/10.1155/2021/8100423
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