A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices

This paper presents chip implementation of the integrated neural recording and stimulation system with stimulation-induced artifact suppression. The implemented chip consists of low-power neural recording circuits, stimulation circuits, and action potential detection circuits. These circuits constit...

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Detalles Bibliográficos
Autores principales: Liu, Xu, Li, Juzhe, Chen, Tao, Wang, Wensi, Je, Minkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416399/
https://www.ncbi.nlm.nih.gov/pubmed/34484653
http://dx.doi.org/10.1155/2021/4153155
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author Liu, Xu
Li, Juzhe
Chen, Tao
Wang, Wensi
Je, Minkyu
author_facet Liu, Xu
Li, Juzhe
Chen, Tao
Wang, Wensi
Je, Minkyu
author_sort Liu, Xu
collection PubMed
description This paper presents chip implementation of the integrated neural recording and stimulation system with stimulation-induced artifact suppression. The implemented chip consists of low-power neural recording circuits, stimulation circuits, and action potential detection circuits. These circuits constitute a closed-loop simultaneous neural recording and stimulation system for biomedical devices, and a proposed artifact suppression technique is used in the system. Moreover, this paper also presents the measurement and experiment results of the implemented 4-to-4 channel neural recording and stimulation chip with 0.18 µm CMOS technology. The function and efficacy of simultaneous neural recording and stimulation is validated in both in vivo and animal experiments.
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spelling pubmed-84163992021-09-04 A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices Liu, Xu Li, Juzhe Chen, Tao Wang, Wensi Je, Minkyu J Healthc Eng Research Article This paper presents chip implementation of the integrated neural recording and stimulation system with stimulation-induced artifact suppression. The implemented chip consists of low-power neural recording circuits, stimulation circuits, and action potential detection circuits. These circuits constitute a closed-loop simultaneous neural recording and stimulation system for biomedical devices, and a proposed artifact suppression technique is used in the system. Moreover, this paper also presents the measurement and experiment results of the implemented 4-to-4 channel neural recording and stimulation chip with 0.18 µm CMOS technology. The function and efficacy of simultaneous neural recording and stimulation is validated in both in vivo and animal experiments. Hindawi 2021-08-27 /pmc/articles/PMC8416399/ /pubmed/34484653 http://dx.doi.org/10.1155/2021/4153155 Text en Copyright © 2021 Xu Liu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liu, Xu
Li, Juzhe
Chen, Tao
Wang, Wensi
Je, Minkyu
A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title_full A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title_fullStr A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title_full_unstemmed A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title_short A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices
title_sort neural recording and stimulation chip with artifact suppression for biomedical devices
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416399/
https://www.ncbi.nlm.nih.gov/pubmed/34484653
http://dx.doi.org/10.1155/2021/4153155
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