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Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells

METHODS: Hypoxia in hBMSCs was induced for 0, 4, and 12 hours, and cellular senescence was evaluated by senescence-associated β-galactosidase (SA-β-gal) staining. Tandem mass tag (TMT) labeling was combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for differential proteomic ana...

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Detalles Bibliográficos
Autores principales: Mai, Liping, He, Guodong, Chen, Jing, Zhu, Jiening, Chen, Shaoxian, Hou, Xinghua, Yang, Hui, Zhang, Mengzhen, Wu, Yueheng, Lin, Qiuxiong, Yang, Min, Li, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416403/
https://www.ncbi.nlm.nih.gov/pubmed/34484348
http://dx.doi.org/10.1155/2021/5555590