Cargando…

miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway

BACKGROUND: Atherosclerosis is a chronic process that takes place in the vascular wall and causes various cardiovascular diseases (CVDs). Micro-RNA-149 (miR-149) mediates many physiological and pathological processes, including atherosclerosis. However, it is unclear about the roles of miR-149 in en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Zhongsheng, Li, Jinyu, Tong, Rui, Zhang, Xiaorong, Yu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416406/ https://www.ncbi.nlm.nih.gov/pubmed/34484820 http://dx.doi.org/10.1155/2021/9963258

Ejemplares similares

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway
por: Zhu, Zhongsheng, et al.
Publicado: (2019)

Astragaloside IV Protects Against Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Endothelial Cell Injury by Reducing Oxidative Stress and Inflammation
por: Zhu, Zhongsheng, et al.
Publicado: (2019)

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
por: Fan, Xiaodi, et al.
Publicado: (2015)

MicroRNA-155 promotes ox-LDL-induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway
por: Yin, Shuangshuang, et al.
Publicado: (2018)

An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E(-/-) mice
por: Peng, Nan, et al.
Publicado: (2014)

Inhibition of Connexin 43 reverses ox-LDL-mediated inhibition of autophagy in VSMC by inhibiting the PI3K/Akt/mTOR signaling pathway
por: Qin, Xuqing, et al.
Publicado: (2022)

miR-155 Promotes ox-LDL-Induced Autophagy in Human Umbilical Vein Endothelial Cells
por: Zhang, Zhaozhi, et al.
Publicado: (2017)

MiR-483-5p downregulation alleviates ox-LDL induced endothelial cell injury in atherosclerosis
por: Zhu, Hezhong, et al.
Publicado: (2023)

Ox-LDL-mediated ILF3 overexpression in gastric cancer progression by activating the PI3K/AKT/mTOR signaling pathway
por: Sun, Danping, et al.
Publicado: (2022)

Impaired Autophagy Induced by oxLDL/β2GPI/anti-β2GPI Complex through PI3K/AKT/mTOR and eNOS Signaling Pathways Contributes to Endothelial Cell Dysfunction
por: Zhang, Guiting, et al.
Publicado: (2021)

Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway
por: Li, Xiao-yu, et al.
Publicado: (2017)

Dihydroartemisinin Induces Endothelial Cell Autophagy through Suppression of the Akt/mTOR Pathway
por: Liu, Jing, et al.
Publicado: (2019)

mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes
por: Sohrabi, Yahya, et al.
Publicado: (2019)

miR-183-96-182 clusters alleviated ox-LDL-induced vascular endothelial cell apoptosis in vitro by targeting FOXO1
por: Liu, Zhi-Qin, et al.
Publicado: (2018)

Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis
por: Zhou, Hongyi, et al.
Publicado: (2021)

Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells
por: Yao, Jinpeng, et al.
Publicado: (2016)

miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway
por: Wang, Liang, et al.
Publicado: (2019)

Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling
por: Tang, Yanghua, et al.
Publicado: (2021)

Up-regulated miR-106b inhibits ox-LDL-induced endothelial cell apoptosis in atherosclerosis
por: Zhang, Yunqing, et al.
Publicado: (2020)

MiR-146b inhibits autophagy in prostate cancer by targeting the PTEN/Akt/mTOR signaling pathway
por: Gao, Song, et al.
Publicado: (2018)

Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR
por: Huangfu, Yaru, et al.
Publicado: (2023)

Zhilong Huoxue Tongyu Capsule Alleviated the Pyroptosis of Vascular Endothelial Cells Induced by ox-LDL through miR-30b-5p/NLRP3
por: Liu, Mengnan, et al.
Publicado: (2022)

Brazilian Green Propolis Inhibits Ox-LDL-Stimulated Oxidative Stress in Human Umbilical Vein Endothelial Cells Partly through PI3K/Akt/mTOR-Mediated Nrf2/HO-1 Pathway
por: Yuan, Wenwen, et al.
Publicado: (2019)

miR-214 ameliorates sepsis-induced acute kidney injury via PTEN/AKT/mTOR-regulated autophagy
por: Sang, Zhenzhen, et al.
Publicado: (2021)

ASK1 Mediates Apoptosis and Autophagy during oxLDL-CD36 Signaling in Senescent Endothelial Cells
por: Cho, KyoungJoo, et al.
Publicado: (2019)

Mingmu Xiaomeng Tablets Restore Autophagy and Alleviate Diabetic Retinopathy by Inhibiting PI3K/Akt/mTOR Signaling
por: Fang, Yuwei, et al.
Publicado: (2021)

BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
por: Xiao, Quan, et al.
Publicado: (2022)

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway
por: Duan, Junchao, et al.
Publicado: (2014)

Autophagy promotes angiogenesis via AMPK/Akt/mTOR signaling during the recovery of heat-denatured endothelial cells
por: Liang, Pengfei, et al.
Publicado: (2018)

Correction: MiR-146b inhibits autophagy in prostate cancer through affecting PTEN/AKT/mTOR signaling pathway
por: Gao, Song, et al.
Publicado: (2019)

mTOR, autophagy, and reprogramming
por: Tang, Bor Luen
Publicado: (2014)

Ox-LDL modifies the behaviour of bone marrow stem cells and impairs their endothelial differentiation via inhibition of Akt phosphorylation
por: Chu, Ling, et al.
Publicado: (2011)

Shikonin Alleviates Endothelial Cell Injury Induced by ox-LDL via AMPK/Nrf2/HO-1 Signaling Pathway
por: Liu, Shuang, et al.
Publicado: (2021)

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition
por: Lakhani, Ronak, et al.
Publicado: (2014)

Suppression of sirtuin 1 alleviates airway inflammation through mTOR-mediated autophagy
por: Wu, Yuanyuan, et al.
Publicado: (2020)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Ox-LDL increases OX40L in endothelial cells through a LOX-1-dependent mechanism
por: Dong, Q., et al.
Publicado: (2013)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

Inhibition of miR-214-3p Protects Endothelial Cells from ox-LDL-Induced Damage by Targeting GPX4
por: Xie, Min, et al.
Publicado: (2021)

HMGB1 promotes Ox-LDL-induced endothelial cell damage by inhibiting PI3K/Akt signaling pathway
por: Huo, Xin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_93l6avb67p06gr9868fah81fsp