Cargando…

Targeting cancer stem cells via integrin β4

Integrins mediate cell-cell interactions and communication with the extracellular matrix (ECM). These transmembrane protein receptors allow binding between a cell and its surroundings, initiating a breadth of intracellular signaling resulting in proliferation, differentiation, survival, or migration...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dobson, Hannah E., Ruan, Shasha, Chang, Alfred E., Wicha, Max S., Li, Qiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2021
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416562/ https://www.ncbi.nlm.nih.gov/pubmed/34504657 http://dx.doi.org/10.18632/oncotarget.27977

Ejemplares similares

Targeting cancer stem cells via dendritic-cell vaccination
por: Teitz-Tennenbaum, Seagal, et al.
Publicado: (2012)

Development and Application of Cancer Stem Cell-Targeted Vaccine in Cancer Immunotherapy
por: Lin, Ming, et al.
Publicado: (2017)

The Role of Integrins in Cancer and the Development of Anti-Integrin Therapeutic Agents for Cancer Therapy
por: Lu, Xinjie, et al.
Publicado: (2008)

Promise of cancer stem cell vaccine
por: Zhou, Li, et al.
Publicado: (2015)

Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells
por: Wang, Su He, et al.
Publicado: (2013)

Integrins as architects of cell behavior
por: Streuli, Charles H.
Publicado: (2016)

Precision health for breast cancer metastasis: biomaterial scaffolds as an engineered metastatic niche to define, study, and monitor metastatic progression
por: Bushnell, Grace G., et al.
Publicado: (2019)

Cancer Stem Cells Therapeutic Target Database: The First Comprehensive Database for Therapeutic Targets of Cancer Stem Cells
por: Hu, Xiaoqing, et al.
Publicado: (2016)

New Perspectives on the Role of Integrin-Linked Kinase (ILK) Signaling in Cancer Metastasis
por: McDonald, Paul C., et al.
Publicado: (2022)

Cancer stem cell heterogeneity in hereditary breast cancer
por: Wicha, Max S
Publicado: (2008)

Simultaneous destabilization of β-catenin and Ras via targeting of the axin-RGS domain as a potential therapeutic strategy for colorectal cancer
por: Cha, Pu-Hyeon, et al.
Publicado: (2016)

Two cancer stem cell‐targeted therapies in clinical trials as viewed from the standpoint of the cancer stem cell model
por: Caras, Ingrid W.
Publicado: (2020)

Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancer
por: Song, In-Sung, et al.
Publicado: (2015)

Metabolic plasticity of cancer stem cells
por: Luo, Ming, et al.
Publicado: (2015)

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
por: Li, Qiao, et al.
Publicado: (2014)

Chemokines and cellular plasticity of ovarian cancer stem cells
por: Zou, Weiping, et al.
Publicado: (2015)

Migratory gene expression signature predicts poor patient outcome: Are cancer stem cells to blame?
por: Wicha, Max S
Publicado: (2012)

Pancreatic cancer microenvironment, to target or not to target?
por: Carr, Ryan M, et al.
Publicado: (2016)

The Impact of the “Yogic Lifestyle” on Cancer Prognosis and Survival: Can we Target Cancer Stem Cells with Yoga?
por: Beri, Kavita
Publicado: (2017)

Development of 'synthetic lethal' strategies to target BRCA1-deficient breast cancer
por: Wicha, Max S
Publicado: (2009)

The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1
por: Morris, Gavin E., et al.
Publicado: (2022)

Mammary stem cell number as a determinate of breast cancer risk
por: Ginestier, Christophe, et al.
Publicado: (2007)

Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells
por: Lu, Lin, et al.
Publicado: (2015)

Cancer stem cell marker CD90 inhibits ovarian cancer formation via β3 integrin
por: Chen, Wei-Ching, et al.
Publicado: (2016)

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β
por: Parvani, Jenny G., et al.
Publicado: (2013)

Dipping cells in acidic bath could make stem cells
por: Chen, Jinhui, et al.
Publicado: (2014)

Exploring Integrins in Smooth Muscle Function: Addressing Challenging Levels of Complexity and Deciphering Organ-specific Codes of Contraction?
por: Hennenberg, Martin
Publicado: (2022)

β1 Integrins as Therapeutic Targets to Disrupt Hallmarks of Cancer
por: Blandin, Anne-Florence, et al.
Publicado: (2015)

Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
por: Wicha, Max S
Publicado: (2006)

Correction for Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β
Publicado: (2014)

A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4
por: Liu, ShuYan, et al.
Publicado: (2016)

Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits
por: Ma, Binbin, et al.
Publicado: (2019)

Tumor Targeting via Integrin Ligands
por: Marelli, Udaya Kiran, et al.
Publicado: (2013)

Dysregulated PJA1-TGF-β signaling in cancer stem cell–associated liver cancers
por: Chen, Jian, et al.
Publicado: (2020)

Roles of Integrin α6β4 Glycosylation in Cancer
por: Kariya, Yoshinobu, et al.
Publicado: (2017)

GD2+ cancer stem cells in triple-negative breast cancer: mechanisms of resistance to breast cancer therapies
por: Nguyen, Khoa, et al.
Publicado: (2022)

Lymphoma stem cells: A step toward a new therapeutic target
por: Kim, Seok Jin
Publicado: (2011)

Hematopoietic Stem/Progenitor Cells Directly Contribute to Arteriosclerotic Progression via Integrin β(2)
por: Wang, Xuhong, et al.
Publicado: (2015)

β1-Integrin and Integrin Linked Kinase Regulate Astrocytic Differentiation of Neural Stem Cells
por: Pan, Liuliu, et al.
Publicado: (2014)

Effects of β4 integrin expression on microRNA patterns in breast cancer
por: Gerson, Kristin D., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_k8jqd5sj2pkabgsgbjqouequmb