Cargando…

Therapeutic effects, immunogenicity and cytotoxicity of a cell penetrating peptide-peptide nucleic acid conjugate against cagA of Helicobacter pylori in cell culture and animal model

BACKGROUND AND OBJECTIVES: Helicobacter pylori causes several gastrointestinal diseases, including asymptomatic gastritis, chronic peptic ulcer, duodenal ulcer, lymphoma of the mucosa-associated lymphoid tissue (MALT), and gastric adenocarcinoma. In recent years, failure to eradicate H. pylori infec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farahani, Narges Nodeh, Kalani, Behrooz Sadeghi, Monavari, Seyed Hamidreza, Mirkalantari, Shiva, Montazer, Fatemeh, Sholeh, Mohammad, Javanmard, Zahra, Irajian, Gholamreza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416595/ https://www.ncbi.nlm.nih.gov/pubmed/34540175 http://dx.doi.org/10.18502/ijm.v13i3.6399

Ejemplares similares

Genotyping of Listeria monocytogenes isolates by high-resolution melting curve (HRM) analysis of tandem repeat locus
por: Narimisa, Negar, et al.
Publicado: (2022)

Mixed Infection with cagA Positive and cagA Negative Strains of Helicobacter pylori Lowers Disease Burden in The Gambia
por: Secka, Ousman, et al.
Publicado: (2011)

Characterizing Helicobacter pylori cagA in Myanmar
por: Myint, Thein, et al.
Publicado: (2018)

Cag Type IV Secretion System: CagI Independent Bacterial Surface Localization of CagA
por: Kumar, Navin, et al.
Publicado: (2013)

CagA(+) Helicobacter pylori, Not CagA(–) Helicobacter pylori, Infection Impairs Endothelial Function Through Exosomes-Mediated ROS Formation
por: Xia, Xiujuan, et al.
Publicado: (2022)

Role of CagA in H. pylori gastric cancer
Publicado: (2013)

EPIYA motiefs of cagA and upper gastrointestinal diseases
por: Soleiman-Meigooni, Saeed, et al.
Publicado: (2015)

Proteomic Characterization of Helicobacter pylori CagA Antigen Recognized by Child Serum Antibodies and Its Epitope Mapping by Peptide Array
por: Akada, Junko, et al.
Publicado: (2014)

Evolution of cagA Oncogene of Helicobacter pylori through Recombination
por: Furuta, Yoshikazu, et al.
Publicado: (2011)

Conformational Analysis of Isolated Domains of Helicobacter pylori CagA
por: Woon, Amanda P., et al.
Publicado: (2013)

Evaluating the relationship between serum immunoglobulin G (IgG) and A (IgA) anti-CagA antibody and the cagA gene in patients with dyspepsia
por: Fakhre-Yaseri, Hashem, et al.
Publicado: (2017)

An RGD Helper Sequence in CagL of Helicobacter pylori Assists in Interactions with Integrins and Injection of CagA
por: Conradi, Jens, et al.
Publicado: (2012)

Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila
por: Reid, David W., et al.
Publicado: (2012)

Helicobacter pylori cagA gene variants in Malaysians of different ethnicity
por: Mohamed, Ramelah, et al.
Publicado: (2009)

Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein
por: Suzuki, Nobumi, et al.
Publicado: (2015)

Fragmentation of CagA Reduces Hummingbird Phenotype Induction by Helicobactor pylori
por: Chang, Chih-Chi, et al.
Publicado: (2016)

Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation
por: Zhao, Qing, et al.
Publicado: (2018)

Evolutionary mechanism leading to the multi-cagA genotype in Helicobacter pylori
por: Su, Hanfu, et al.
Publicado: (2019)

Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria
por: Yordanov, Daniel, et al.
Publicado: (2017)

Construction, Cloning, and Expression of CagA Recombinant Protein of Helicobacter pylori
por: Shapouri Moghaddam, Abbas, et al.
Publicado: (2020)

Functional antagonism between CagA and DLC1 in gastric cancer
por: Hinsenkamp, Isabel, et al.
Publicado: (2022)

Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold
por: Zhao, Xing-Liang, et al.
Publicado: (2015)

Role of Cell-Penetrating Peptides in Intracellular Delivery of Peptide Nucleic Acids Targeting Hepadnaviral Replication
por: Ndeboko, Bénédicte, et al.
Publicado: (2017)

Helicobacter pylori Infection in Thailand: A Nationwide Study of the CagA Phenotype
por: Uchida, Tomohisa, et al.
Publicado: (2015)

Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA
por: Shimoda, Asako, et al.
Publicado: (2016)

The Role of H. pylori CagA in Regulating Hormones of Functional Dyspepsia Patients
por: Meng, Wang-Ping, et al.
Publicado: (2016)

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients
por: Archampong, Timothy N., et al.
Publicado: (2017)

Cell Penetrating Peptide Conjugated Chitosan for Enhanced Delivery of Nucleic Acid
por: Layek, Buddhadev, et al.
Publicado: (2015)

Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges
por: Huang, Yue-Wern, et al.
Publicado: (2015)

Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori
por: Backert, Steffen, et al.
Publicado: (2011)

Helicobacter pylori CagA Disrupts Epithelial Patterning by Activating Myosin Light Chain
por: Muyskens, Jonathan B., et al.
Publicado: (2011)

Inhibitory Effects of Anthocyanins on Secretion of Helicobacter pylori CagA and VacA Toxins
por: Kim, Sa-Hyun, et al.
Publicado: (2012)

Clinical relevance of the cagA, tnpA and tnpB genes in Helicobacter pylori
por: Abadi, Amin Talebi Bezmin, et al.
Publicado: (2014)

The CagA toxin of Helicobacter pylori: abundant production but relatively low amount translocated
por: Jiménez-Soto, Luisa F., et al.
Publicado: (2016)

Influence of H. pylori CagA Coupled with Alcohol Consumption on Cytokine Profiles in Men
por: Qu, Baoge, et al.
Publicado: (2016)

Epidemiology of Helicobacter pylori and CagA-Positive Infections and Global Variations in Gastric Cancer
por: Park, Jin Young, et al.
Publicado: (2018)

Prevalence of Helicobacter pylori cagA and iceA Genes and Their Association with Gastrointestinal Diseases
por: Abu-Taleb, Ashwak M. F., et al.
Publicado: (2018)

CagA increases DNA methylation and decreases PTEN expression in human gastric cancer
por: Zhang, Baogui, et al.
Publicado: (2019)

Western-Type Helicobacter pylori CagA are the Most Frequent Type in Mongolian Patients
por: Tserentogtokh, Tegshee, et al.
Publicado: (2019)

Helicobacter pylori CagA induced interleukin-8 secretion in gastric epithelial cells
por: Fazeli, Zeinab, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ik52an2vpq2elkbnht84nuug3a