Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers

Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene’s unusual electronic structure, speci...

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Autores principales: Xu, Zhenglei, Peng, Minsi, Zhang, Zhuliang, Zeng, Haotian, Shi, Ruiyue, Ma, Xiaoxin, Wang, Lisheng, Liao, Bihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416602/
https://www.ncbi.nlm.nih.gov/pubmed/34490213
http://dx.doi.org/10.3389/fchem.2021.733371
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author Xu, Zhenglei
Peng, Minsi
Zhang, Zhuliang
Zeng, Haotian
Shi, Ruiyue
Ma, Xiaoxin
Wang, Lisheng
Liao, Bihong
author_facet Xu, Zhenglei
Peng, Minsi
Zhang, Zhuliang
Zeng, Haotian
Shi, Ruiyue
Ma, Xiaoxin
Wang, Lisheng
Liao, Bihong
author_sort Xu, Zhenglei
collection PubMed
description Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene’s unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer.
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spelling pubmed-84166022021-09-05 Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers Xu, Zhenglei Peng, Minsi Zhang, Zhuliang Zeng, Haotian Shi, Ruiyue Ma, Xiaoxin Wang, Lisheng Liao, Bihong Front Chem Chemistry Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene’s unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer. Frontiers Media S.A. 2021-08-19 /pmc/articles/PMC8416602/ /pubmed/34490213 http://dx.doi.org/10.3389/fchem.2021.733371 Text en Copyright © 2021 Xu, Peng, Zhang, Zeng, Shi, Ma, Wang and Liao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Xu, Zhenglei
Peng, Minsi
Zhang, Zhuliang
Zeng, Haotian
Shi, Ruiyue
Ma, Xiaoxin
Wang, Lisheng
Liao, Bihong
Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title_full Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title_fullStr Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title_full_unstemmed Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title_short Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers
title_sort graphene-assisted electrochemical sensor for detection of pancreatic cancer markers
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416602/
https://www.ncbi.nlm.nih.gov/pubmed/34490213
http://dx.doi.org/10.3389/fchem.2021.733371
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