Discordant immunohistochemistry in an unusual MLH1 gene variant in a case of Lynch syndrome

Immunohistochemistry for mismatch repair proteins and microsatellite instability testing are recommended screening methods for Lynch syndrome. They have a good sensitivity and specificity, allowing for directed genetic testing and diagnosis. We report a case of Lynch syndrome with retained MMR prote...

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Detalles Bibliográficos
Autores principales: Nagabhushana, Prerana, Kumari, Snigdha, Rohilla, Minakshi, Srinivasan, Radhika, Arora, Aashima, Rastogi, Pulkit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Reports and Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416636/
https://www.ncbi.nlm.nih.gov/pubmed/34504932
http://dx.doi.org/10.1016/j.gore.2021.100854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416636/
https://www.ncbi.nlm.nih.gov/pubmed/34504932
http://dx.doi.org/10.1016/j.gore.2021.100854

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