SARS-CoV-2 viral RNA levels are not 'viral load'

Ct values are commonly used as proxies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 'viral load'. Since coronaviruses are positive single-stranded RNA [(+)ssRNA] viruses, current reverse transcription (RT)-qPCR target amplification does not distinguish replicative from t...

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Detalles Bibliográficos
Autores principales: Michalakis, Yannis, Sofonea, Mircea T., Alizon, Samuel, Bravo, Ignacio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416646/
https://www.ncbi.nlm.nih.gov/pubmed/34535373
http://dx.doi.org/10.1016/j.tim.2021.08.008

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