Preclinical and clinical progress for HDAC as a putative target for epigenetic remodeling and functionality of immune cells

Genetic changes are difficult to reverse; thus, epigenetic aberrations, including changes in DNA methylation, histone modifications, and noncoding RNAs, with potential reversibility, have attracted attention as pharmaceutical targets. The current paradigm is that histone deacetylases (HDACs) regulat...

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Detalles Bibliográficos
Autores principales: Zhang, Sijia, Zhan, Lingjun, Li, Xue, Yang, Zhenhong, Luo, Yumin, Zhao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416716/
https://www.ncbi.nlm.nih.gov/pubmed/34512154
http://dx.doi.org/10.7150/ijbs.62001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416716/
https://www.ncbi.nlm.nih.gov/pubmed/34512154
http://dx.doi.org/10.7150/ijbs.62001

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